The ancient Chinese recognized goiter and the therapeutic effects of burnt sponge and seaweed in reducing its size or causing its disappearance. The modern use of iodine in the prevention of goiter dates from , when it was proposed that goiter is an iodine deficiency disease due to lack of iodine in the water supply.
But unfavorable symptoms of iodism were frequent owing to overenthusiastic use and overdose of iodine. Consequently, iodide prophylaxis was discredited and abandoned. The presence of iodine in organic combination as a normal constituent of the thyroid was established in and the use of iodine in treatment and prevention of goiter was revived.
In the general use of iodized salt in goitrous areas was shown to be effective in preventing simple endemic goiter. View Author Information.
Cite this: J. Article Views Altmetric -. Citations Abstract The ancient Chinese recognized goiter and the therapeutic effects of burnt sponge and seaweed in reducing its size or causing its disappearance. Cited By. This article is cited by 35 publications.
Analytical Chemistry , 88 2 , Journal of Chemical Education , 87 7 , Dasgupta , Yining Liu and Jason V.
Molecular iodine mediated transition-metal-free oxidative dehydrogenation of 4,7- dihydro pyrazolo[3,4- b ]pyridines. Synthetic Communications , 79 , Decato , Eric A. John , Orion B. Halogen Bonding: An Introduction. Jamshidi , Gholam Reza Rokni Lamouki. An algorithmic treatment strategy for the inhibition of type-II deiodinase enzyme on thyroid secretion hormones. Biomedical Signal Processing and Control , 66 , Fahey , Frederick D.
Celebrating eighty years of radionuclide therapy and the work of Saul Hertz. Journal of Applied Clinical Medical Physics , 22 1 , Risk assessment of iodine intake from the consumption of red seaweeds Palmaria palmata and Chondrus crispus. Environmental Science and Pollution Research , 27 36 , Multinodular Goiter. Ganesan , Uma Tiwari , Gaurav Rajauria. Seaweed nutraceuticals and their therapeutic role in disease prevention.
Food Science and Human Wellness , 8 3 , Iodine deficiency remains one of the most important public health issues globally, and an estimated 2. In , the United Nations World Summit for Children set forth the goal of eliminating iodine deficiency worldwide [ 29 ], and considerable progress has since been achieved. Other groups which have been instrumental in advocating for improved iodine nutrition have been Kiwanis International and the U.
Center for Disease Control [ 16 ]. A public health approach has been used to help ensure adequate iodine intake in U. The U. National Academy of Sciences also advocates that iodine be included in all prenatal multivitamins [ 33 ]. Following the successful implementation of salt iodization program in Switzerland, the introduction of iodized table salt in the U.
However, although recent national studies demonstrate that the general population is overall iodine sufficient, salt iodization in the U. National Center for Biotechnology Information , U. Journal List Nutrients v. Published online Nov Angela M. Braverman , and Elizabeth N. Author information Article notes Copyright and License information Disclaimer. This article has been corrected. See Nutrients. This article has been cited by other articles in PMC.
Abstract Iodine is a micronutrient required for thyroid hormone production. Keywords: history, iodine, supplementation. Importance of Adequate Iodine Nutrition Adequate levels of iodine, a trace element variably distributed on the earth and found mostly in the soil and water of coastal areas, are required for the synthesis of the thyroid hormones, thyroxine T4 and triiodothyronine T3 , which play key roles in the metabolic processes of vertebrate life.
Sources of Iodine Intake and Exposure Iodine atomic weight Dietary Iodine In the U. Iodine Fortification and Supplementation in the U. Iodized Salt In the U. Iodine in Supplements and Multivitamins Iodine is required for normal brain myelination in utero and during the early post-partum period. Current Status of and Recommendations for Iodine Nutrition Levels of urinary iodine cannot be used to determine iodine status in an individual, given the day-to-day variation in dietary iodine intake.
Conclusions The U. Conflict of Interest The authors declare no conflict of interest. References 1. Rosenfeld L. Discovery and early uses of iodine. Carpenter K. David Marine and the problem of goiter. Chatin A. Merke F. History of endemic cretinism. In: Merke F. History and Iconography of Endemic Goiter and Cretinism.
Hans Huber Publishers; Berne, Switzerland: Dasgupta P. Iodine nutrition: Iodine content of iodized salt in the United States. Boddie R. Germicidal activities of representatives of five different teat dip classes against three bovine mycoplasma species using a modified excised teat model.
Dairy Sci. Murray C. Pearce E. He found that certain solutions of potassium iodide were capable of dissolving more iodine Lugol's solution which he felt "augmented the potency of the remedy.
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